منابع مشابه
Brainstem Gliomas
Diffuse intrinsic pontine glioma (DIPG) is the most common type representing approximate‐ ly 80% of brainstem gliomas [5, 6]. They have a dismal prognosis with a median survival of only a year. Their natural history is often compared to but worse than that of supratentorial glioblastoma seen primarily in the adult population. Nondiffuse brainstem gliomas, includ‐ ing focal, dorsal exophytic and...
متن کاملFocal brainstem gliomas
ةيلمعلا ءانثأ ريوصتلا كلذكو ةروطتلما ةيبصعلا ةحلالما ةمظنأ حارج ةردق نم تززع ةيبصعلا ةيجولويزيفلا دصرلا ايجولونكتو يفو ،ةيرؤبلا غامدلا عذج ماروأ لاصئتسا نم باصعلأاو خلما هذه .ةحارجلل ةلباق ريغ ةرشتنلما غامدلا عذج ماروأ ربتعت لباقلما ،ينثحابلا سفنل اًقباس ترشن ةساردل ًارارمتسا ةيملعلا ةقرولا .غامدلا عذج ماروأ ريوصت اضيأو فينصتو صيخشت تشقان عذج ماروأ ةحارج بيلاسأو قرط نافلؤلما حرشي ةلاقلما هذه يف ء...
متن کاملRole of surgery in brainstem gliomas.
For a pediatric neurosurgeon, one of the most frustrating experiences is managing a child with brainstem glioma. With a median survival of less than 12 months, these children are often managed with radiation therapy and sometimes with chemotherapy. Most tumors in the pediatric population are of diffuse variety (60-75% of the brainstem tumors) occurring in the pons and only a selective percentag...
متن کاملBrainstem gliomas--retrospective analysis of 86 patients.
Brainstem gliomas constitute 10% of brain tumors in children and less than 2% in adults. Since therapeutic options are limited and brainstem gliomas are associated with a high morbidity and mortality, we sought to analyze the prognostic factors associated with a better outcome. We reviewed the records of 86 patients with brainstem gliomas treated between 1996 and 2006. We recorded demographic a...
متن کاملGenetic and immune features of resectable malignant brainstem gliomas
We surveyed common genetic mutations (IDH1, H3F3A, PPM1D, and TP53) and immune features (PD-L1 expression and CD8+ T cell tumor infiltration) in a series of 62 malignant brainstem gliomas that were resected via microsurgery. IDH1 mutations were mutually exclusive with H3F3A mutations. IDH1 mutations appeared only in adults and occurred more frequently in tumors larger than 10cm3 (8/29 vs 1/32, ...
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ژورنال
عنوان ژورنال: Journal of Neurosurgery
سال: 2012
ISSN: 0022-3085,1933-0693
DOI: 10.3171/2012.3.jns12590